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That said, body weight can influence side effects and the pace of titration

The primary completion of TRIUMPH-1 is expected around May 2026, with NDA submission projected for Q4 2026 to Q1 2027

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When BCBS covers Zepbound, typical PA requirements include: BMI 30 or 27 with a comorbidity (hypertension, type 2 diabetes, high cholesterol, or OSA), 6 months of documented lifestyle modification (diet and exercise program), and sometimes step therapy requiring trial of other weight loss medications first

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